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Table 1 Demographic and clinical characteristics of the study cohort by diagnosis

From: Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation

  Control (N = 11) DS/AD (N = 9)a TSC (N = 10) FTD (N = 5)b
Age (Mean, SD) 52 (9) 53 (6) 49 (6) 69 (4)
Race (N, percent)
 Black 1 (9%) 1 (11%) 0 (0%) 0 (0%)
 White 8 (73%) 8 (89%) 10 (100%) 4 (80%)
 Unable to determine 2 (18%) 0 (0%) 0 (0%) 1 (20%)
 Sex (percent female) 46% 56% 50% 80%
Epilepsy diagnosis (N, Percent)
 Epilepsy present 0 (0%) 2 (22%) 5 (50%) 0 (0%)
 Epilepsy absent 11 (100%) 6 (67%) 3 (30%) 5 (100%)
 Unable to Determine 0 (0%) 1 (11%) 2 (20%) 0 (0%)
 IDD diagnosis (N, Percent) 0 (0%)    
 IDD Present 0 (0%) 0 (0%) 5 (55%) 0 (0%)
 IDD Absent 11 (100%) 8 (89%) 3 (33%) 5 (100%)
 Unable to determine 0 (0%) 1 (11%) 2 (22%) 0 (0%)
  1. IDD Intellectual or developmental disability
  2. aThree subjects carried a clinical diagnosis of Down Syndrome
  3. bFour subjects had progressive supranuclear palsy (PSP), one had FTLD-tau, unclassified