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Table 6 Association between area deprivation and TDP-43 neuropathological changes

From: Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study

Adjusted Odds

Limbic-Predominant Age-Related TDP-43 Encephalopathy

Odds Ratios

CI

IMD Stratum 2 vs 1

0.76

0.38 – 1.48

IMD Stratum 3 vs 1

0.77

0.35 – 1.67

IMD Stratum 4 vs 1

0.65

0.25 – 1.64

IMD Stratum 5 vs 1

0.84

0.36 – 1.95

Covariates:

  

 Age at Death

1.07

1.03 – 1.11

 APOE ε4 Carrier

1.59

0.94 – 2.67

 Diabetes

1.01

0.44 – 2.35

 Hypertension

0.45

0.27 – 0.77

 Male Sex

1.29

0.75 – 2.23

 Smoker

0.96

0.56 – 1.64

 Alcohol Misuse

0.57

0.19 – 1.66

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Acta Neuropathologica Communications

ISSN: 2051-5960

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