Fig. 1From: RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulationArchitechture of RyR1 channel. A Schematic diagram of the domain architecture of RyR1. B Coulombic density map of RyR1 (PDBID: 7M6A). The accessory protein calstabin-1 is shown in yellow. Zoom in showing Calcium (C), ATP (D), and caffeine (E) binding sites with the coordinating residues [14, 76]Back to article page