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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: CNS tumors with YWHAE:NUTM2 and KDM2B-fusions present molecular similarities to extra-CNS tumors having BCOR internal tandem duplication or alternative fusions

Fig. 1

Radiological and histopathological features. A Axial T1-weighted sequence with gadolinium showing an enhanced extra-axial left temporal mass. B Compact tumor with undifferentiated morphology (HPS, magnification × 400). C No immunoexpression of GFAP (magnification × 400). D Expression of BCOR in tumor cells (magnification × 400). E Axial T1-weighted sequence with gadolinium showing an enhancing polycystic mass in the right parietal lobe. F Proliferation composed of pseudorosettes (HPS, magnification × 400). G Focal expression of GFAP (magnification × 400). H BCOR immunoexpression in a part of tumor cells (magnification × 400). I Axial tomodensitometry with contrast showing a hemorrhagic lesion of the left parietal lobe with slight contrast enhancement. J Proliferation composed of pseudorosettes (HPS, magnification × 400). K Absence of immunoexpression of GFAP (magnification × 400). L Expression of BCOR (magnification × 400). M Sagittal T1-weighted sequence with gadolinium showing an enhancing multinodular lesion of the pons. N Compact tumor with nodular arrangement of undifferentiated cells (HPS, magnification × 400). O No immunoexpression of GFAP (magnification × 400). P No immunoexpression of BCOR (magnification × 400). Black scale bars represent 50 µm. Each line represents a case: Case 1 for A-D pictures; Case 2 for E–H pictures, Case 3 for I-L pictures, and Case 4 for M-P pictures. HPS: Hematoxylin Phloxin Saffron

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