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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology

Fig. 6

Location of medial temporal lobe (MTL) subregion, Brodmann Area 35 (BA35), defined histologically in eleven specimens and mapped into the space of the MRI atlas. Different color labels are used to indicate the type of sulcal pattern each speciemen has: type 1, deep continuous sulcus; type 2, discontinuous sulcus with shallower anterior branch. Panels A and B each show a cross-sectional view through the MTL at an anterior and more posterior level respectively. Each panel includes a heat map (top-left corner) showing the degree of overlap across the different specimens. The bottom row demonstrates the variability in the location of specific anatomical bondaries between different specimens. Note that boundaries in which a background label is adjacent to a non-background label are not considered, i.e. in some cases, the ERC label is adjacent to the background instead of the para-subiculum. (ERC entorhinal cortex, ParaSUB para-subiculum, BA Brodmann Area)

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