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Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice

Fig. 10

Comparison of the magnitude of differential gene expression between AD-tau injected 5XFAD × TREM2+/+ (WT) mice and 5XFAD × TREM2−/− (bi-allelic KO) or 5XFAD × TREM2+/− (mono-allelic KO) mice in the cortex (a) and hippocampus (b). Genes with an absolute logFC > 1.5 are annotated. Grey = non-significant difference; Yellow = Significant difference between TREM+/+ and TREM2+/−; Blue = Significant difference between TREM+/+ and TREM2−/−; Green = Significant in both previous comparisons

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Acta Neuropathologica Communications

ISSN: 2051-5960

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