Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies

Table 3 Summary of cases from the University of Pennsylvania Tissue Bank used in this study

Case	Clinical diagnosis	Pathological diagnosis	Amyloid score (Thal)	Braak	CERAD	Gender	Age	PMI (hrs)
MSA-8	Spinocerebellar ataxia	MSA	1	II	sparse	Female	76	12
MSA-9	MSA-C	MSA	0	0	none	Male	68	8
MSA-10	MSA-C	MSA	0	II	none	Male	72	9
LBD-6	PD	LBD diffuse neocortical	2	III/IV	frequent	Female	82	5
LBD-7	DLB	LBD diffuse neocortical	1	I/II	none	Male	68	15
LBD-8	Corticobasal syndrome	LBD diffuse neocortical	3	I/II	moderate	Male	83	20

Listed are the clinical and pathological diagnoses, the sex, age at death, amyloid score (Thal), Braak stage and CERAD ratings. DLB dementia with Lewy body, LBD Lewy body dementia, MSA-C multiple system atrophy with predominant cerebellar ataxia, MSA-P multiple system atrophy with predominant Parkinsonism, PD Parkinson’s disease, PMI postmortem interval

ISSN: 2051-5960