Fig. 2
Quantification of frontal cortical pericytes in dementias and ageing controls. A-B, Individual data points and box plots showing number of pericytes per COL4 area (mm2) (A) and per unit (mm) capillary length (B). Dots demonstrate distribution of pericytes in all the cases and controls whereas box plots represent mean distribution of pericytes within cases. Per Methods, pericytes were determined in capillaries within regions free of infarcts or CAA. Mean pericyte numbers were increased in PSND, PSD, Mixed and AD compared to older control subjects (***P < 0.001 Control vs PSND and PSD; **P < 0.01 Control vs Mixed and AD). The mean numbers were also greater in young controls compared to older controls. (***P < 0.001). VaD group showed similar pericyte number to controls (P > 0.05)