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Table 3 Partial Spearman correlations of semiquantitative MTL scores of neurodegenerative pathologies with MTL subregional thickness measures in different subgroups, including only tau in the model

From: Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions

 

ERC

BA35

BA36

PHC

SUB

CA1

SRLM

Sample size

55

53

53

56

58

58

57

Tau in full dataset

 − 0.27a

 − 0.30*

0.04

 − 0.06

 − 0.13

 − 0.18

 − 0.31*

Sample size

33

31

32

34

35

35

34

Tau in A-subset

 − 0.31a

 − 0.37*

 − 0.06

0.14

 − 0.22

 − 0.30a

 − 0.15

Sample size

25

23

24

26

27

27

26

Tau in A-/TDP-subset

 − 0.45*

 − 0.52*

 − 0.08

 − 0.09

 − 0.44*

 − 0.45*

 − 0.38a

  1. All models are corrected for age, sex and hemisphere
  2. ap < 0.10; *p < 0.05; **p < 0.01; ***p < 0.001. Significant results are bolded. ERC entorhinal cortex, BA Brodmann area, PHC parahippocampal cortex, SUB subiculum, CA cornu ammonis, SRLM stratum radiatum lacunosum moleculare
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Acta Neuropathologica Communications

ISSN: 2051-5960

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