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Table 3 Partial Spearman correlations of semiquantitative MTL scores of neurodegenerative pathologies with MTL subregional thickness measures in different subgroups, including only tau in the model

From: Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions

  ERC BA35 BA36 PHC SUB CA1 SRLM
Sample size 55 53 53 56 58 58 57
Tau in full dataset  − 0.27a  − 0.30* 0.04  − 0.06  − 0.13  − 0.18  − 0.31*
Sample size 33 31 32 34 35 35 34
Tau in A-subset  − 0.31a  − 0.37*  − 0.06 0.14  − 0.22  − 0.30a  − 0.15
Sample size 25 23 24 26 27 27 26
Tau in A-/TDP-subset  − 0.45*  − 0.52*  − 0.08  − 0.09  − 0.44*  − 0.45*  − 0.38a
  1. All models are corrected for age, sex and hemisphere
  2. ap < 0.10; *p < 0.05; **p < 0.01; ***p < 0.001. Significant results are bolded. ERC entorhinal cortex, BA Brodmann area, PHC parahippocampal cortex, SUB subiculum, CA cornu ammonis, SRLM stratum radiatum lacunosum moleculare