Fig. 2
From: Neuropathological hallmarks of fetal hydrocephalus linked to CCDC88C pathogenic variants
Main neuropathological hallmarks of hydrocephalus linked to CCDC88C pathogenic variants. a Accumulation of fluid (asterisk) under the choroid epithelium causing collapse of the villus mesenchymatous core which contains collapsed vessels (arrow) [H&E, OM × 200]. b Compared with the normal choroid villus morphology in an age- matched control [H&E, OM × 200]. c Without disruption of the basal lamina as evidenced by Jones’ silver impregnation method [H&E, OM × 200]. d Covered by epithelial cells still containing glycogen [PAS, OM × 200]. H&E: Hematoxylin and eosin stain; OM: original magnification; PAS: periodic Schiff staining