Fig. 3
From: The degree of astrocyte activation is predictive of the incubation time to prion disease
Changes in gene expression profiles detected with the Astrocyte panel in prion-infected mice. (a) Ordered heat map of grouped samples for cortex (Ctx), hypothalamus (HTh), thalamus (Th) and hippocampus (Hp) of normal and terminally ill females (F) and males (M) inoculated via i.p. (upper panel) or i.c. (lower panel) with ME7, 22L, RML, or SSLOW, as described in Materials and Methods. (b) Venn diagram for DEGs (linear fold change ≥  ± 1.2; n = 3; p < 0.05) in cortex (left) and thalamus (right) of i.c. inoculated ME7, 22L, RML, or SSLOW mice (females and males, n = 3 + 3)