Fig. 3

Spinal homogenates from paralyzed H46R rats seed G85R-SOD1:YFP mice inefficiently. a Scatter plot of the ages at which G85R-SOD1:YFP mice developed paralysis or were euthanized after injection of spinal homogenates from paralyzed H46R rats. b, c Representative images of inclusion pathology seen in paraffin sections from the spinal cord of G85R-SOD1:YFP mice that had been injected with spinal homogenates from heterozygous and homozygous paralyzed H46R rats, with a fivefold concentrated inoculum prepared from homogenate from a paralyzed homozygous rat (images representative of 2–3 sections per mouse). Raw data provided in Additional file 1: Data File 1. Scale bar = 100 µm (b) or 50 µm (c)