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Table 1 Characteristics of subjects by diabetes status

From: Brain insulin signaling and cerebrovascular disease in human postmortem brain

  Total Diabetes No Diabetes
n = 150 n = 75 n = 75
Demographic
 Age-at-death in years, mean (SD) 86.6 (6.1) 86.6 (5.9) 86.7 (6.3)
 Women, n (%) 72 (48%) 36 (48%) 36 (48%)
 Education in years, mean (SD) 18.1 (3.3) 18.2 (3.1) 18.1 (3.4)
 APOE ε4, n (%) 36 (24%) 15 (20%) 21 (28%)
Neuropathologic
Brain infarcts (presence), n (%)
 Any type infarct (by size and location)
  One infarct 29 (19%) 13 (17%) 16 (21%)
  More than one infarct 46 (31%) 32 (43%) 14 (19%)
 Gross infarcts
  One infarct 28 (19%) 14 (19%) 14 (19%)
  More than one infarct 28 (19%) 19 (25%) 9 (12%)
 Microinfarcts
  One infarct 26 (17%) 16 (21%) 10 (13%)
  More than one infarct 19 (14%) 12 (16%) 7 (9%)
 Cortical infarcts
  One infarct 20 (13%) 12 (16%) 8 (11%)
  More than one infarct 15 (11%) 9 (12%) 6 (8%)
 Subcortical infarcts
  One infarct 28 (19%) 16 (21%) 12 (16%)
  More than one infarct 30 (20%) 22 (29%) 8 (11%)
Cerebral vessel pathologies
 Atherosclerosis
  Mild 71 (47%) 31 (41%) 40 (53%)
  Moderate 49 (33%) 25 (33%) 24 (32%)
  Severe 12 (8%) 8 (11%) 4 (5%)
 Arteriolosclerosis
  Mild 44 (30%) 25 (33%) 19 (25%)
  Moderate 31 (21%) 12 (16%) 19 (25%)
  Severe 15 (10%) 12 (16%) 3 (4%)
 Cerebral amyloid angiopathy
  Mild 39 (27%) 31 (41%) 29 (39%)
  Moderate 31 (21%) 14 (19%) 17 (23%)
  Severe 15 (10%) 6 (8%) 9 (12%)
Alzheimer’s disease pathology
 Global score 0.6 (0.6) 0.7 (0.6) 0.6 (0.5)