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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein

Fig. 1

Amylin, α-synuclein, tau and PrP immunoreactivity in endocrine pancreatic cells. Immunohistochemistry for amylin (ad), α-synuclein (eh), Tau (il), and PrP (mp) in pancreatic cells from subjects with a normal neuropathological examination and no history of T2DM (a, c, i, m), with a normal neuropathological examination and history of T2DM (b, f, j, n), with Parkinson`s disease (PD), dementia with Lewy bodies (DLB) or incidental Lewy body disease (ILBD) (c, g, k, o) or with Alzheimer’s disease (AD) (d, h, l, p): 40 × magnification; scale bar = 50 µm. Violin plots showing amylin (q), α-synuclein (r), Tau (s) and PrPc (t) immunoreactivity quantification in endocrine pancreatic cells: **: p ≤ 0.05, ***: p ≤ 0.001; ****: p ≤ 0.0001

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