Table 1 Study groups and treatment combinations
From: Chronically altered NMDAR signaling in epilepsy mediates comorbid depression
Group | SE induction | Chronic phase (daily i.p. injections for 10Â days) | Acute phase (two i.p. injections 30Â min prior to FST2) |
|---|---|---|---|
Sham | No | saline | saline + saline |
Saline | Yes | saline | saline + saline |
NI | Yes | saline | 15 mg/kg NI + saline |
Flxa | Yes | saline | saline + 10 mg/kg Flx |
Flxa + NI | Yes | saline | 15 mg/kg NI + 10 mg/kg Flx |
Flxc | Yes | 10 mg/kg Flx | saline + saline |
Flxc + NI | Yes | 10 mg/kg Flx | 15 mg/kg NI + saline |