Fig. 3

(a) Fitted probabilities according to the stratified Cox proportional hazards model of overall survival (OS) for 215 glioblastoma patients with regard to the cumulative number [n] of ‘methylated’ CpG sites (violet: n = 25, light blue: n = 20, blue: n = 15, red: n = 10, green: n = 5, orange: n = 0). (b) Kaplan–Meier curves of overall survival for 113 glioblastoma patients with MSP-positive tumors (dotted blue line) substratified for the cumulative number [n] of ‘methylated’ CpG sites (light blue line: n ≥ 18, dark blue line: n < 18)