Fig. 8
From: Alzheimer’s disease brain contains tau fractions with differential prion-like activities
AD tau fractions induce tau pathology differentially in vivo. a, b AD tau fractions at similar tau levels were injected into hippocampus of 18-month-old-FVB mice. Brain sections were immunostained with AT8 3 months after injection. Hoechst dye was used to stain nuclei. Representative AT8 immunostaining of ipsilateral (Ips) and contralateral (Cont) CA1s (a) and Ips CA3 (b) of the mouse hippocampus after injection with AD tau fractions. c AT8-positive neurons in Ips hippocampus (left) and Cont hippocampus (right) were quantified. Data are presented as mean ± SD, **P<0.05; **P<0.01