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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Alzheimer’s disease brain contains tau fractions with differential prion-like activities

Fig. 5

AD tau fractions capture tau differentially. a Schematic of tau capture assay. b Various mounts of AD tau fractions were dotted onto NC membrane. After blocking, the membranes were incubated with cell extract containing HA-tau151-391, and the captured tau was detected by anti-HA, followed by HRP-2nd antibody and ECL. c Levels of tau in the fractions were analyzed by immuno-dot-blots developed with the mixture of R134d and 92e. d Levels of tau captured by the four tau fractions derived from the same AD cerebral cortex were plotted against the level of the dotted tau. e Levels of tau captured by O-tau, SI1-tau, and SI2-tau from three AD brains. The data are presented as mean ± SD. **p < 0.05

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