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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer’s disease

Fig. 3

Representative overview (scale bar = 2000 μm) and high magnification (insert, scale bar = 50 μm) images of AT8 staining in APP V717I mutation carrier for the hippocampus (a), superior temporal gyrus (b) and visual cortex (c) reveal substantial NFT pathology in all regions examined. (d) AT8 staining also reveals “frequent” neuritic plaques in the inferior temporal cortex (scale bar = 1000 μm, insert scale bar = 50 μm). Representative overview (scale bar = 2000 μm) and high magnification (insert, scale bar = 50 μm) images of TDP-43 staining demonstrate TDP-43 positive inclusions in hippocampus (e) and amygdala (f)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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