Fig. 4

B and plasma cells are virtually absent from the CP. a Examples of CD19+ and CD138+ cells in the CP of progressive MS patients; basement membrane was immunolabeled with collagen IV. White arrowhead in the top panel points to a CD19+ CD138+ cell; in the lower panel, a CD19+ B cell is seen. b Density of CP CD19+ cells in the different CP compartments (Wilcoxon rank sum test with continuity correction). c Density of CP CD138+ cells in the different CP compartments (Wilcoxon rank sum test with continuity correction). PMS: progressive MS. Scale bars are 50 μm