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Table 1 HD and Control Patient Data

From: Single-nucleus RNA-seq identifies Huntington disease astrocyte states

PatientAgeGenderCAG RepeatsOther NeuropathologyCause of DeathRNASeqPMICOLDPMIFROZEN
HD549348F46–25Glial scars, dentate, cerebellum, smallPE, pneumoniaSN + BULKN/A9:33
HD557571M44–18AA, H/I acuteCardiac ArrestSN + BULK0:0715:04
HD530154M46–19AA, H/I acuteN/ABULK1:2718:52
HD492950M49–16H/I acuteInanitionBULK0:0543:08
C538262M AAAcute,PESN + BULKN/A5:24
C540454F AAAcute, MISN + BULK6:4116:36
C481236M H/I acuteAcute, MIBULKN/A8:37
C18052F AA, H/I acute, infarcts, C, precentral gyrusN/ABULK2:256:07
C9855M AAAcute collapseBULK6:0537:00
C451856M AA, focal, old hem & infarcts, thalamus, stem, basal gangliaAcute cardiac arrestBULKN/A8:50
  1. PE Pulmonary embolism, MI Myocardial infarction, AA Athero-arteriosclerosis, NS No other significant neuropathology, H/I Hypoxic/ischemic changes, C Caudate, N/A Not available. PMICOLD hours between death and preservation of brain on ice. PMIFROZEN hours between preservation on ice and freezing. Note that some of these patients died outside of Columbia University Medical Center and brains were sent here on ice. Cause of death was not available for some patients who died outside the medical center and whose autopsy was limited to the brain