Fig. 5

GABA neurons in the ECx of DSCAML1^GT2/GT2 and DSCAML1^{A2105T2/A2105T} mice. a–d Distribution of inhibitory (GAD67-positive) neurons in the ECx of the indicated genotypes at PD20 (a, b) and PD2 (c, d). Arrows indicate small clusters of GABAergic neurons in IER. e–j Morphological changes of inhibitory neurons due to DSCAML1 deficiency. Photo of the limbic area of the distribution of GFP-positive (GAD67-positive) neurons in WT; GAD67^GFP/+ mouse (e, g) and Dscaml1^GT2/GT2; GAD67^GFP/+ mouse (f, h) in the lateral ECx at PD2 of each indicated genotypes. Scale bars: 100 µm (e, f), 1000 µm (g, h). i, j GABA neurons in the lateral ECx are decreased in Dscaml1^A2105T mouse at PD2. Scale bars: 100 µm