Table 1 Dose-dependent onset of clinical rabies signs after i.m. application of rRABV Dog in the upper hind leg muscle of 6- to 8-week old BALB/c mice
From: Neuroglia infection by rabies virus after anterograde virus spread in peripheral neurons
Virus dose | Euthanized | Salivary gland | Oral swab |
|---|---|---|---|
TCID50/mouse | (Humane endpoint reached) | Virus RNA | Virus RNA |
3000 | 6/6 | 6/6 | 5*/6 |
300 | 5/6 | 5/6 | 5/6 |
30 | 5/6 | 5/6 | 5/6 |
3 | 2/6 | 2/6 | 2/6 |