All | PD cases | Controls | AD cases | Non-neurodegenerativea | |
---|---|---|---|---|---|
N | 1960 | 700 | 564 | 386 | 310 |
Age (years, 95% CI) | 69.3 (62.0–75.0) | 66.2 (59.6–73.3) | 70.0 (64.9–74.3) | 75.0 (70.0–80.0) | 64.0 (55.0–73.0) |
Males (N, %) | 1107 (56.5%) | 435 (62.1%) | 297 (52.7%) | 222 (57.5%) | 153 (49.4%) |
Alpha-Synuclein (ZScore(pg/mL)) | − 0.02 (− 0.67 to 0.65) | − 0.03 (− 0.70 to 0.60) | 0.02 (− 0.71 to 0.71) | 0.14 (− 0.57 to 0.80) | − 0.23 (− 0.76 to 0.47) |
Amyloid Beta (ZScore(pg/mL)) | − 0.20 (− 0.72 to 0.64) | − 0.20 (− 0.72 to 0.45) | 0.11 (− 0.52 to 1.04) | − 0.63 (− 1.00 to − 0.25) | 0.03 (− 0.49 to 0.90) |
Total Tau (ZScore(pg/mL)) | − 0.27 (− 0.66 to 0.40) | − 0.27 (− 0.70 to 0.39) | − 0.34 (− 0.67 to 0.28) | 0.22 (− 0.41 to 1.00) | − 0.50 (− 0.73 to − 0.08) |
Phosphorylated Tau (ZScore(pg/mL)) | − 0.25 (− 0.69 to 0.42) | − 0.30 (− 0.72 to 0.35) | − 0.27 (− 0.70 to 0.35) | 0.22 (− 0.42 to 0.95) | − 0.48 (− 0.81 to − 0.04) |