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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain

Fig. 5

Quantification of perfused vessels after microembolization in vivo. a Example (maximum intensity projections) of (i) a microsphere (white) with lectin perfusion despite the presence of a microsphere, and (ii) a microsphere causing vascular nonperfusion (asterisk) using i.v. lectin (red) at the day of killing and postmortem laminin staining (green). Scale bar = 50 µm. b Quantification of vascular nonperfusion at D1, 3 and 7 for 15 µm (black boxes) and 25 µm microspheres (grey boxes). Three animals were excluded from perfusion analysis because the i.v. lectin injection failed, resulting in n = 5–6 animals per time point. Data are depicted as median and IQR (min–max). *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA with Tukey–Kramer’s test for multiple comparisons

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