Fig. 3
From: Is the eye a window to the brain in Sanfilippo syndrome?
Evaluation of retinal ganglion cells, amacrine cells, bipolar cells and horizontal cells in three to 25 week old unaffected and MPS IIIA mouse retina. Representative images of RBPMS-immunolabelled retinal ganglion cells (a, b), calretinin-immunolabelled amacrine cells (d, e), PKCα-immunolabelled rod bipolar cells (g, h) and calbindin-immunolabelled horizontal cells (j, k) are shown. Arrows indicate examples of the cell type quantified. Quantification of retinal ganglion cells (c), amacrine cells (f), rod bipolar cells (i) and horizontal cells (l). Scale bar; a, b = 25 µm; d, e, g, h, j, k = 50 µm. Data are expressed as mean ± SEM. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, the outer nuclear layer. *p < 0.05, **p < 0.01