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Table 4 Intermediate repeat length allele frequencies in different age groups of controls

From: Carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population

 

18–65 years

66–84 years

85–105 years

p valuea

Longer allele

 7–45

273 (31%)

656 (33%)

363 (33%)

0.46

 17–45

29 (3.3%)

44 (2.2%)

28 (2.5%)

0.33

 21–45

18 (2.1%)

29 (1.5%)

19 (1.7%)

0.62

 24–45

12 (1.4%)

17 (0.86%)

14 (1.3%)

0.92

 24–30

10 (1.1%)

9 (0.46%)

11 (1.0%)

0.85

Two 7–45 alleles

26 (3.0%)

51 (2.6%)

27 (2.5%)

0.48

Longer allele in individuals with two 7–45 alleles

 7–16

23 (2.6%)

47 (2.4%)

24 (2.2%)

 

 ≥ 17

3 (0.34%)

4 (0.20%)

3 (0.27%)

 ≥ 21

1 (0.11%)

2 (0.10%)

0

 ≥ 24

0

1 (0.050%)

0

N of age group

873

1973

1102

 
  1. aCochran–Armitage trend test. Excluded 10 individuals from whom age group was unknown