Fig. 1
From: Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD
Sequence identity of human UBQLN isoforms and expression levels of WT hUBQLN1 and the P497S mutant hUBQLN2 transgenes in Tg mice. a Sequence identity of human UBQLN isoforms with one another. b Strategy of the mouse cross used to generate the four genotypes for the study. c Graph showing the relative mRNA expression levels of human UBQLN1 and the P497S mutant UBQLN2 transgenes in the brain of 24-week-old animals measured by RT qPCR analysis. d Comparison of P497S transgene mRNA expression by RT qPCR analysis of 24-week-old male and female mice