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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

Fig. 7

Electrophysiological analysis of DPR expressing larvae. a Excitatory junction potential (EJP) amplitude, b input resistance (Ri), c mini-EJP (mEJP) amplitutde, d mEJP frequency and e Quantal Content measured at muscle 6 (hemi-segment A3/4) of third instar wandering larvae pan-neuronally expressing (nSyb-Gal4) DPRs or an mCD8-GFP control. f representative traces showing evoked (EJP) (top traces) and spontaneous (mEJP) (bottom traces) responses in control (mCD8-GFP) and AP1000 larvae. n’s are shown on each graph. Recordings were made from at least 5 animals (N = 5) taken from at least 3 independent crosses per genotype

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