Table 1 Distributions of neuronal and glial tau aggregations
Regions | NI | Grain | Glial inclusions |
|---|---|---|---|
Frontal cortex | + | − | + |
Primary motor cortex | ++ | − | ++ |
Temporal cortex | + | +* | + |
Insula | ++ | − | ++ |
Subiculum/CA1 | ++ | ++ | ++ |
CA2-4 | + | ++ | + |
Dentate gyrus | + | − | + |
Parahippocampal cortex | ++ | ++ | ++ |
Amygdala | ++ | + | ++ |
Temporal tip | ++ | − | ++ |
Parietal cortex | + | − | + |
Occipital cortex | + | − | + |
Neostriatum | ++ | − | ++ |
Globus pallidus | ++ | − | ++ |
Basal nucleus of Meynert | ++ | − | ++ |
Cerebral white matter | − | − | ++ |
Pars reticulata of substantia nigra | ++ | − | ++ |
Pars compacta of substantia nigra | + | − | + |
Tegmentum of midbrain | ++ | − | ++ |
Locus ceruleus | + | − | + |
Pontine nucleus | + | − | + |
Medullary reticular formation | ++ | − | ++ |
Anterior horn of spinal cord | ++ | − | ++ |
Dorsal horn of spinal cord | + | − | + |