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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease

Fig. 2

Elevated levels of STI1 and Hsp90β in STI1 overexpressing 5xFAD mice (TgA-5xFAD). a Representative immunoblots from hippocampal lysates obtained from 3 to 5-month-old male 5xFAD and TgA-5xFAD mice for STI1. b Protein levels of STI1 relative to actin and normalized to 5xFAD control. c Representative immunoblots and quantification from hippocampal lysates obtained from 3 to 5-month-old male 5xFAD and TgA-5xFAD mice for d Hsp90β (previously shown to be increased in plain TgA mice) e and Hsp70. All data are mean ± SEM and were analyzed using unpaired t-test. At least 5 mice were used for each genotype. Experiments were repeated at least twice. *p < 0.05, **p < 0.01, ***p < 0.0001. Raw data available at: https://doi.org/10.6084/m9.figshare.12115704

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