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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

Fig. 7

Laminin and fibronectin staining in HBVSMC cultures after 72 h exposure to normoxia and hypoxia. Reference images (a – c) show the presence of smooth muscle actin in the HBVSMCs used in this study. The pattern of laminin staining (e,k) was similar in the HBVSMC cultures but there was a significant increase in expression with increased levels of CO2(l) compared to normoxice cultures (f). Fibronectin staining (h,n) had a web-like appearance in both cultures but staining appeared more intense in the normoxic cultures (i) compared to cultures exposed to increased levels of CO2(o). Cell density, indicated by DAPI stained nuclei (d, g, j, m), did not appear to be altered in normoxic conditions or conditions of increased levels of CO2. Scale bar = 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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