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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Molecular identification of CNS NB-FOXR2, CNS EFT-CIC, CNS HGNET-MN1 and CNS HGNET-BCOR pediatric brain tumors using tumor-specific signature genes

Fig. 6

Morphology of CNS HGNET-MN1 tumors. a Elongated cells with abundant eosinophilic cytoplasm and prominent processes radiating towards blood vessels. b Astroblastoma-type perivascular pseudorosettes with hyaline sclerosis. c Perivascular formations of ribbon-like appearance. d Areas with distinct papillary structure. e Advanced hyalinization of vascular stroma and perivascular orientation of neoplastic cells producing a papillary architecture. f Extensive hyalinization of fibrovascular stroma. g, h The solid growth pattern with papillary formation and microcystic changes. i Densely packed, round to ovoid cells with scanty cytoplasm and high mitotic activity. The scale bars: a-e, g-i - 50 μm; f - 100 μm

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