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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma

Fig. 2

T-distributed stochastic neighbor embedding (t-SNE) plots of MYCN amplified cases. a. t-SNE plot demonstrating spatial separation of MYCN amplified ependymomas (black circle) from the previously described ependymoma subcategories in the DKFZ reference dataset. Seven of 8 cases show tight clustering. One case (case 4) is located outside the main cluster (red arrow). b. t-SNE plot demonstrating anomalous clustering of case 4 away from the main MYCN amplified cluster (black circle) and at the periphery of the mesenchymal glioblastoma cluster in DKFZ reference dataset (red arrow)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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