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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies

Fig. 5

Tau phosphorylated at Ser208 is present in pathological inclusions of PS19 and rTg4510 transgenic mouse models of tauopathies. Staining of pSer208 specific antibody 3G12 is abundant in tau inclusions within the (a) hippocampus and (b) cortex of 6 month old rTg4510 tau transgenic mice compared to other phospho-tau specific antibodies AT8, CP13, and 7F2. Staining of pSer208 specific antibody 3G12 is abundant in tau inclusions within the (c) thalamus and (d) brainstem/pons of 12 month old PS19 tau transgenic mice compared to other phospho-tau specific antibodies AT8, CP13, and 7F2. Scale bar shows 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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