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Table 2 Summary statistics from tissue immunohistochemistry image analysis. The table shows the number of individuals and cells counted for each tissue region and subject group. The number of neurons or glial cells and RBM45 nuclear and cytoplasmic inclusions were counted as described in the Methods section. For each subject, a total of 8 fields per region (hippocampal dentate gyrus or lumbar spinal cord) were evaluated. FTLD-TDP = frontotemporal lobar degeneration with TDP-43 proteinopathy

From: RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases

GroupNTotal CellsMean Cells/ FieldSEM Cells/ FieldMean Nuclear RBM45 Inclusions/CellSEM Nuclear RBM45 Inclusions/CellMean Cytoplasmic RBM45 Inclusions/CellSEM Cytoplasmic RBM45 Inclusions/Cell
Dentate Gyrus Granule Cells
 Control10414551.814.920.440.0900
 AD5159039.758.320.980.340.0440.051
 ALS8294345.985.981.490.270.0480.055
 FTLD-TDP6196240.925.812.380.230.1090.072
Spinal Cord Glial Cells
 Control96939.621.180.230.0600
 ALS15268922.351.741.040.180.110.47
Spinal Cord Motor Neurons
 Control93084.290.530000
 ALS153512.910.42000.150.14