Fig. 2From: RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseasesRBM45 association with nuclear stress bodies is a general response to cellular stress. HEK293 cells were treated as indicated and the distribution of RBM45 and SAFB-positive nuclear stress bodies (NSBs) was evaluated by immunocytochemistry. a In untreated cells, the distribution of RBM45 and SAFB is diffuse and nuclear. b-e Treatment with the indicated stressors results in the formation of RBM45- and SAFB-positive NSBs. For all images, scale bar = 5 μmBack to article page