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Table 1 Demographic characteristics of 8 patients

From: A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma

Patient IDP553P690P701P568P785P712P816P722
Pathology DiagnosisSecondary GBM, WHO Grade 4Secondary GBM, WHO Grade 4Diffuse astrocytoma, WHO Grade 2Diffuse astrocytoma, WHO Grade 2Anaplastic astrocytoma, WHO Grade 3Anaplastic astrocytoma, WHO Grade 3GBM, WHO Grade 4GBM, WHO Grade 4
MGMT StatusLow level detectedDetectedDetectedDetectedNot detectedDetectedDetectedDetected
IDHMutantMutantMutantMutantNot detectedNot detectedNot detectedNot detected
Previous ChemoYesYesNoNoNoNoNoNo
Previous RadiationYesYesNoNoNoNoNoNo
Previous Radiation Dose50.4Gy60GyNANANANANANA
Previous DiagnosisDiffuse astrocytoma, WHO Grade 2Oligoastrocytoma, WHO Grade 2NANANANANANA
Progression Interval (months)3055NANANANANANA
Vital StatusAliveAliveAliveAliveAliveAliveDeceasedDeceased