Table 4 Top genes differentially expressed in oligodendrocytes in MSA vs HC
Genes | Ensembl Gene ID | Biotype | Base Mean | log2 FC | Stat | p | adj p |
|---|---|---|---|---|---|---|---|
GGCX | ENSG00000115486 | Protein Coding | 803.4 | 1.691 | 7.072 | 1.5E-12 | 1.1E-08 |
MOCS1 | ENSG00000124615 | Protein Coding | 405.2 | −1.759 | −6.433 | 1.2E-10 | 4.4E-07 |
NF1 | ENSG00000196712 | Protein Coding | 775.5 | −1.532 | −6.089 | 1.1E-09 | 2.4E-06 |
LINC01572 | ENSG00000261008 | lincRNA | 207.2 | −2.010 | −6.063 | 1.3E-09 | 2.4E-06 |
PRRG3 | ENSG00000130032 | Protein Coding | 269.3 | 1.808 | 5.731 | 1.0E-08 | 1.4E-05 |
HMBOX1 | ENSG00000147421 | Protein Coding | 124.9 | 2.247 | 5.588 | 2.3E-08 | 2.7E-05 |
PLP1 | ENSG00000123560 | Protein Coding | 383.7 | −1.744 | −5.494 | 3.9E-08 | 3.5E-05 |
– | ENSG00000249906 | antisense | 29.0 | 4.224 | 5.495 | 3.9E-08 | 3.5E-05 |
PPP1CA | ENSG00000172531 | Protein Coding | 458.2 | −1.617 | −5.359 | 8.4E-08 | 6.6E-05 |
C8orf88 | ENSG00000253250 | Protein Coding | 46.1 | −2.657 | −5.313 | 1.1E-07 | 7.6E-05 |