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Table 2 Summary of the neuropathological groups used in this study. The number of cases with each observed symptom(s) and respective percentages are indicated (see also Additional file 1-Table A1)

From: Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes

Neuropathological DiagnosisNon-dementedTypical ADFTD symptoms with or without additional AD symptomsn
svPPAsvPPA + ADAD + behaviorAD + motor speechbvFTDPSP
Non-AD20 (100%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)20
p-preAD16 (100%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)16
ADTDP-0 (0%)10 (100%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)10
ADTDP + CTF0 (0%)24 (80%)4 (13,4%)0 (0%)1 (3,3%)1 (3,3%)0 (0%)0 (0%)30
ADTDP + FL0 (0%)7 (63,6%)0 (0%)1 (9,1%)1 (9,1%)0 (0%)2 (18,2%)0 (0%)11
FTLD-TDP0 (0%)0 (0%)3 (30%)0 (0%)1 (10%)0 (0%)5 (50%)1 (10%)10