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Table 2 Summary of the neuropathological groups used in this study. The number of cases with each observed symptom(s) and respective percentages are indicated (see also Additional file 1-Table A1)

From: Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes

Neuropathological Diagnosis

Non-demented

Typical AD

FTD symptoms with or without additional AD symptoms

n

svPPA

svPPA + AD

AD + behavior

AD + motor speech

bvFTD

PSP

Non-AD

20 (100%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

20

p-preAD

16 (100%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

16

ADTDP-

0 (0%)

10 (100%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

10

ADTDP + CTF

0 (0%)

24 (80%)

4 (13,4%)

0 (0%)

1 (3,3%)

1 (3,3%)

0 (0%)

0 (0%)

30

ADTDP + FL

0 (0%)

7 (63,6%)

0 (0%)

1 (9,1%)

1 (9,1%)

0 (0%)

2 (18,2%)

0 (0%)

11

FTLD-TDP

0 (0%)

0 (0%)

3 (30%)

0 (0%)

1 (10%)

0 (0%)

5 (50%)

1 (10%)

10