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Table 4 Semiquantitative analysis of immunoglobulin G isotypes among AQP4-reactive antibodies raised in mimotope-AQP4268–285-immunized Lewis rats

From: Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes

 IgG1IgG2aIgG2bIgG2c
IV-04++++
III-01+(+)+++++++(+)
I-04+++(+)+(+)+
I-13++(+)++++++
  1. + to +++ indicate reactivity of immunoglobulin G isotype-specific antibodies to AQP4-reactive antibodies from mimotope-AQP4268–285-immunized Lewis rats bound to HEK293 cells expressing rat AQP4-EmGFP. The reactivity was rated as + (weak), ++ (moderate), and +++ (strong), respectively