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Table 5 Summary of data for insoluble cytosolic proteins in 13 month old Tet.HuAβ treated with Dox

From: Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis

GenotypesAge assessedTotal Aβ burden assessed by CS-silver stain# Animals# of cytosolic proteins identified as over-represented in SDS insoluble fractions
Pair-wise analysis
Combined with SAINT > 0.9
Tet.HuAβ2.5 mo30
13 mo+++480
13 mo + Dox 1wk+++352
13 mo + Dox 4 wk+++443
NTg2.5 mo-2NA
13 mo-2
13 mo + Dox 1wk-2
13 mo + Dox 4 wk 2