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Table 1 Summary of demographic data

From: Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients

EWAS

Group

Brain Bank

Sex

Age

PMI

 

CTRL

BBH: 9

KCL: 28

M: 19

F: 18

73.0 ± 10.5

42.0 ± 19.2

–

MSA

BBH: 17

KCL: 24

M: 17

F: 24

66.0 ± 5.7

42.0 ± 26.3

–

P

0.150

0.496

7.12E-04

0.999

–

RT-qPCR

Group

Brain Bank

Sex

Age

PMI

RIN

CTRL

BBH: 10

NBB: 10

M: 8

F: 12

73.5 ± 12.0

28.2 ± 27.4

5.3 ± 0.6

MSA

BBH: 16

M: 5

F: 11

64.4 ± 6.0

40.6 ± 20.3

5.1 ± 0.7

P

7.58E-04

0.731

6.53E-03

0.128

0.373

Flow cytometry

Group

Brain Bank

Sex

Age

  

CTRL

BBH: 46

M: 18

F: 28

71.9 ± 9.4

–

–

MSA

BBH: 24

M: 11

F: 13

62.9 ± 7.9

–

–

P

–

0.618

8.46E-05

–

–

  1. Demographic summaries are shown for the cohorts for Illumina MethylationEPIC data (EWAS), RT-qPCR data, and flow cytometric data. Group differences were tested using Fisher’s exact test (sex, origin), or t-tests. Age in years at death is reported; CTRL normal, healthy control, MSA multiple system atropy, BBH Bispebjerg Brain Bank, KCL King’s College London Brain Bank, NBB Netherlands Brain Bank, M male, F female, PMI Post-mortem interval in hours, RIN RNA Integrity Number
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Acta Neuropathologica Communications

ISSN: 2051-5960

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