Fig. 2
From: FGFR- gene family alterations in low-grade neuroepithelial tumors
Histologic features of FGFR-altered LGNTs. Three examples of LGNTs bearing characteristic FGFR-alteration are shown: DNET with FGFR1- TKD (a, b), EVN with FGFR1-TACC1 fusion (c, d), and PLNTY with FGFR2-CTNNA3 fusion (e, f). Note that while histologic features of each lesion met diagnostic criteria in keeping with a specific entity, LGNTs share many overlapping histologic features including bland neurocytic/ oligodedroglioma-like nuclear features and of lack of significant proliferative or mitotic activity