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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing

Fig. 1

Mosaicism for SNCA gains. a, b. Combined FISH and NeuN IHC images of a neuron (a) and a non-neuronal cell (b) from cingulate cortex showing 3 copies of SNCA. Scale bar 5 μm. c, d. The % of mosaicism in cingulate cortex, in neurons (c) and non-neurons (d). p values were corrected for 2 comparisons. e, f. The % of mosaicism in the SN in NM+ cells (e) and NM- cells (f). LB cases included four ILBD and one DLB. The medians and interquartile ranges are shown in (c-f)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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