Fig. 3
From: A metastable subproteome underlies inclusion formation in muscle proteinopathies
Protein supersaturation in hereditary protein aggregate myopathies. Comparison of folded supersaturation scores (σf) between the proteome and proteins enriched in aggregate-containing myofibers (AF) for: (a, b, c) desminopathy (DC: Prt N = 611, Agg N = 6; AF: Prt N = 1387, Agg N = 6), (d, e, f) filaminopathy (DC: Prt N = 333, Agg N = 16; AF: Prt N = 507, Agg N = 16), and (g, h, i) myotillinopathy (DC: Prt N = 680, Agg N = 46; AF: Prt N = 742, Agg N = 46). Box plots and statistical tests as in Fig. 1. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001