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Table 4 Distribution of CD3 (+), CD20 (+), IL-4 (+) and IFNγ (+) cells/mm2 in MS brain tissue

From: Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

 NAWMActive WMLChronic-active WMLNAGMSubpial GML
CD32.0 ± 1.045.6 ± 14.5**19.4 ± 4.2**0.2 ± 0.10.7 ± 0.4
CD201.1 ± 0.44.3 ± 2.52.1 ± 0.60.4 ± 0.20.5 ± 0.3
IL-40.5 ± 0.41.1 ± 1.12.3 ± 0.6*0.0 ± 0.00.0 ± 0.0
IFN-γ0.2 ± 0.15.7 ± 2.8*1.1 ± 0.50.0 ± 0.00.0 ± 0.0
  1. Counts of CD3, CD20 and IL-4 (+) and IFNγ (+) cells in the NAWM (N = 18), active WMLs (N = 10), chronic-active WMLs (N = 7), NAGM (N = 15), subpial GMLs (N = 9). Data is presented as mean +/− SEM
  2. * = p < 0.05, ** < p < 0.01