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Table 4 Distribution of CD3 (+), CD20 (+), IL-4 (+) and IFNγ (+) cells/mm2 in MS brain tissue

From: Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

  NAWM Active WML Chronic-active WML NAGM Subpial GML
CD3 2.0 ± 1.0 45.6 ± 14.5** 19.4 ± 4.2** 0.2 ± 0.1 0.7 ± 0.4
CD20 1.1 ± 0.4 4.3 ± 2.5 2.1 ± 0.6 0.4 ± 0.2 0.5 ± 0.3
IL-4 0.5 ± 0.4 1.1 ± 1.1 2.3 ± 0.6* 0.0 ± 0.0 0.0 ± 0.0
IFN-γ 0.2 ± 0.1 5.7 ± 2.8* 1.1 ± 0.5 0.0 ± 0.0 0.0 ± 0.0
  1. Counts of CD3, CD20 and IL-4 (+) and IFNγ (+) cells in the NAWM (N = 18), active WMLs (N = 10), chronic-active WMLs (N = 7), NAGM (N = 15), subpial GMLs (N = 9). Data is presented as mean +/− SEM
  2. * = p < 0.05, ** < p < 0.01