Fig. 9From: Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathiesSCRN1 binds to phosphorylated tau in AD cortex tissue. Co-IP was performed on fresh frozen frontal cortex tissue from n = 2 AD and n = 2 cognitively normal samples. IP was performed using anti-SCRN1 or rabbit IgG isotype control. SCRN1 pulled down phosphorylated tau in AD cortex samples, but not control cortex samples. Fiftee microgram protein per sample from total homogenate were loaded for inputs. Loading control: GAPDHBack to article page