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Table 1 Baseline clinicopathological features of the 24 patients with PitNETs

From: Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours

 Total of PitNETs (n = 24)
Gender [n (%)]
 Male16 (66.7%)
 Female8 (33.3%)
Current age (yr) [mean ± standard deviation (SD)]51.9 ± 15.1
Age at diagnosis (yr) [mean ± SD]48.8 ± 15.5
Clinical diagnosis [n (%)]
 Acromegaly8 (33.3%)
 NF-PitNET16 (66.7%)
Hyperprolactinaemia at diagnosis [n (%)]8 (33.3%)
Headache [n (%)]8 (33.3%)
Visual Impairment [n (%)]13 (54.2%)
Hypopituitarism at diagnosis [n (%)]11 (45.8%)
Macroadenoma [n (%)]24 (100%)
Suprasellar extension [n (%)]24 (100%)
Cavernous sinus invasion [n (%)]10 (41.7%)
Ki-67 ≥ 3% [n (%)]5 (20.8%)
Mean number of treatments [mean ± SD]1.6 ± 0.9
Mean number of surgeries [mean ± SD]1.2 ± 0.5
Reoperation [n (%)]5 (20.8%)
Hypopituitarism at last follow-up [n (%)]14 (58.3%)
Active disease at last follow-up [n (%)]4 (16.7%)
Follow-up duration (yr) [mean ± SD]2.5 ± 9.1
Pre-operative haematological parameters [mean ± SD]
 Red cell count (1012/L)[Normal range (NR): M 4.4–5.8 / F 3.95–5.15]4.58 ± 0.46
 Haemoglobin (g/L)[NR: M 130–170 / F 115–155]132.46 ± 12.47
 Haematocrit (%)[NR: M 37–50 / F 33–45]40.24 ± 3.79
 White cell count (109/L)[NR: 3.0–10.0]7.08 ± 3.39
 Neutrophil count (109/L)[NR: 2.0–7.5]3.73 ± 1.51
 Lymphocyte count (109/L)[NR: 1.2–3.65]2.71 ± 2.25
 Monocyte count (109/L)[NR: 0.2–1.0]0.44 ± 0.13
 Eosinophil count (109/L)[NR: 0.0–0.4]0.17 ± 0.11
 Basophil count (109/L)[NR: 0.0–0.1]0.03 ± 0.02
 Platelet count (109/L)[NR: 150–400]234.96 ± 62.18