Table 1 Baseline clinicopathological features of the 24 patients with PitNETs
From: Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours
Total of PitNETs (n = 24) | ||
|---|---|---|
Gender [n (%)] | ||
Male | 16 (66.7%) | |
Female | 8 (33.3%) | |
Current age (yr) [mean ± standard deviation (SD)] | 51.9 ± 15.1 | |
Age at diagnosis (yr) [mean ± SD] | 48.8 ± 15.5 | |
Clinical diagnosis [n (%)] | ||
Acromegaly | 8 (33.3%) | |
NF-PitNET | 16 (66.7%) | |
Hyperprolactinaemia at diagnosis [n (%)] | 8 (33.3%) | |
Headache [n (%)] | 8 (33.3%) | |
Visual Impairment [n (%)] | 13 (54.2%) | |
Hypopituitarism at diagnosis [n (%)] | 11 (45.8%) | |
Macroadenoma [n (%)] | 24 (100%) | |
Suprasellar extension [n (%)] | 24 (100%) | |
Cavernous sinus invasion [n (%)] | 10 (41.7%) | |
Ki-67 ≥ 3% [n (%)] | 5 (20.8%) | |
Mean number of treatments [mean ± SD] | 1.6 ± 0.9 | |
Mean number of surgeries [mean ± SD] | 1.2 ± 0.5 | |
Reoperation [n (%)] | 5 (20.8%) | |
Hypopituitarism at last follow-up [n (%)] | 14 (58.3%) | |
Active disease at last follow-up [n (%)] | 4 (16.7%) | |
Follow-up duration (yr) [mean ± SD] | 2.5 ± 9.1 | |
Pre-operative haematological parameters [mean ± SD] | ||
Red cell count (1012/L) | [Normal range (NR): M 4.4–5.8 / F 3.95–5.15] | 4.58 ± 0.46 |
Haemoglobin (g/L) | [NR: M 130–170 / F 115–155] | 132.46 ± 12.47 |
Haematocrit (%) | [NR: M 37–50 / F 33–45] | 40.24 ± 3.79 |
White cell count (109/L) | [NR: 3.0–10.0] | 7.08 ± 3.39 |
Neutrophil count (109/L) | [NR: 2.0–7.5] | 3.73 ± 1.51 |
Lymphocyte count (109/L) | [NR: 1.2–3.65] | 2.71 ± 2.25 |
Monocyte count (109/L) | [NR: 0.2–1.0] | 0.44 ± 0.13 |
Eosinophil count (109/L) | [NR: 0.0–0.4] | 0.17 ± 0.11 |
Basophil count (109/L) | [NR: 0.0–0.1] | 0.03 ± 0.02 |
Platelet count (109/L) | [NR: 150–400] | 234.96 ± 62.18 |