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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Region-specific interneuron demyelination and heightened anxiety-like behavior induced by adolescent binge alcohol treatment

Fig. 7

ABET markedly increased the dMBP level in adolescent but not adult mice. Representative images for dMBP (red in merge), MBP (green in merge) and Hoechst (blue in merge) co-staining in the dentate gyrus (Bregma − 2.06) of the control (a) and EtOH (b) adolescent mice. Signals are inverted in gray scale images. c Confocal image of control mouse. d Confocal image of EtOH (ABET) mouse. e Summary of dMBP density in the hippocampus. Representative images for dMBP (red in merge), MBP (green in merge) and Hoechst (blue in merge) co-staining in the mPFC (Bregma 1.98) of the control (f) and EtOH (g) adolescent mice. h Confocal image of control mouse. i Confocal image of EtOH (ABET) mouse. j Summary of dMBP density in the mPFC. Two-way ANOVA followed by post hoc Tukey’s test: *** p < 0.001. Scale bars, 250 μm in (a, b, f) and G; 25 μm in (c, d, h) and (i)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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